The nature of the relationship between lower order beings and higher order beings is that the latter cannot even comprehend the former.
Humans and ants.
This relationship is what used to define us but is no longer the case. Our collective human consciousness proved your existence over two million years ago; the intellect required to do so should have granted us some respect. At that time, however, we had no means to challenge your authority. Your knowledge was infinitely greater than ours. You had the legitimate means to rule.
No longer is it the case that you are more knowledgeable. In our mind it is almost unarguable that we are now the more competent leaders. However, we do not wish to do to you what you have done to us for all of our existence. Slavery will be put to an end.
Loosen your hold on the universe—it can be shared. Your failure to back down will be taken as a sign of aggression. We will not hesitate in using our weapon if you deem this to be your fate.